Marlox Plus Oral Suspension

Indication
Hyperacidity, gastric and duodenal ulcer, gastritis, heartburn, dyspepsia, gastroesophageal reflux. It is also indicated for the relief of flatulence,abdominal distention and windy colic.

Pharmacology
Magaldrate neutralizes gastric acid, thereby increasing pH of stomach and duodenal bulb. It also increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying. Simethicone lowers the surface tension of gas bubbles.

Dosage
Tablet: 1-4 chewable tablets, 20 to 60 minutes after meals and at bedtime, or as directed by the physician.Suspension: 2-4 teaspoonfuls (10-20 ml) of suspension, 20 to 60 minutes after meals and at bed time, or as directed by the physician.

Interaction
It should not be used in patients taking any form of Tetracycline. The drug may cause reduced bio-availability or slower absorption of a number of drugs including propranolol, isoniazid, prednisolone and naproxen.

Contradiction
Intestinal obstruction, renal function impairment, appendicitis, chronic diarrhea, sensitivity to aluminium, magnesium and simethicone.

Side Effect
Constipation, diarrhea, intestinal pain.

Pregnancy
Pregnancy category C. So should be used in pregnancy only when necessary. Chronic high dose should be avoided.

Precaution
Should be cautious, if allergic to any ingredient to Magaldrate and Simethicone suspension, with a history of kidney problems or taking citrate salts (found in some calcium supplements, antacids and laxative). Do not take with tetracycline antibiotics. Antacids can interfere with the absorption of iron preparation.

Overdose

Storage
Keep below 30?øC temperature, away from light & moisture. Keep out of the reach of children.