Lindex® 1g Injection: Each vial contains Cephradine with L-Arginine sterile powder equivalent to Cephradine BP 1 g.
Dosage and Administration
The dosage may be given without regard to meals. Adult:Oral: The usual dose is 1 to 2 gm daily in 2 to 4 divided doses. In severe and chronic infection, the dose can be increased up to 4 gm daily, which should be given in equally divided doses. Injection: The usual dose is 2 to 4 gm daily in 3 to 4 equally divided doses by deep intramuscular or intravenous route. Dose may be increased to 8 gm daily in severe infections e.g. septicaemia and endocarditis. Special dose: In urinary tract infection, the usual dose is 500 mg every 12 hours. In respiratory tract and skin & skin structure infection, the usual dose is 250 mg every 6 hours or 500 mg every 12 hours. In lobar pneumonia, the usual dose is 500 mg every 6 hours or 1 gm every 12 hours. Children: Oral: The usual dose is 25 to 50 mg/kg/day, up to 100 mg/kg daily in severe infection, in 2 to 4 equally divided doses. Injection: The usual dose is 50 to 100 mg/kg/day in 4 equally divided doses. Dose may be increased up to 200-300 mg/Kg/day in severe infection. Surgical Prophylaxis: Recommended dose is 1 to 2 gm by intramuscular or intravenous (over 3 to 5 minutes) route. Subsequent parenteral or oral doses can be administered as appropriate. Therapy should be continued for a minimum of 48 to 72 hours after the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. Patients with renal impairment: The following initial dosage schedule is suggested as a guideline based on creatinine clearance. Further modification in the dosage schedule may be required because of individual variations in absorption.
Intramuscular Injection: Add 2 ml of Water for Injection to 500 mg vial and 4 ml of Water for Injection to 1 gm vial and shake. Intravenous Injection: Add 5 ml of Water for Injection to 500 mg vial and 10 ml of Water for Injection to 1 gm vial and shake. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period.
|Medicine Formation||IV Injection|
|Manufactured By||Rangs Pharma|