Inflect tablet consists of an immediate release Esomeprazole magnesium layer and an enteric coated Naproxen core. The enteric coating prevents the release of Naproxen at pH levels below 5.5. As a result Esomeprazole is released first into the stomach, prior to the dissolution of Naproxen in the small intestine. Naproxen is a NSAID with analgesic and antipyretic properties. The mechanism of action of the Naproxen anion, like other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cells. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.
|Manufactured By||Kemico Pharma|