Evit soft 400 Capsule (Liquid Filled)

Indication
As dietary supplement: Vitamin E deficiency resulting from impaired absorption Increased requirements due to diet rich in polyunsaturated fats For healthy hair & skin As an antioxidant Hemolytic anemia due to Vitamin E deficiency Therapeutic use: Cardiovascular disease Heavy metal poisoning Hepatotoxin poisoning Hemolytic anemia Oxygen therapy In nutritional deficiency states.

Pharmacology
Vitamin E acts as an antioxidant in the body. Vitamin E protects polyunsaturated fatty acids (which are components of cellular membrane) and other oxygen-sensitive substances such as vitamin A & vitamin C from oxidation. In premature neonates irritability, edema, thrombosis and hemolytic anemia may be caused due to vitamin E deficiency. Creatinuria, ceroid deposition, muscle weakness, decreased erythrocyte survival or increased in vitro hemolysis by oxidizing agents have been identified in adults and children with low serum tocopherol concentrations.

Dosage
Betterment of cardiovascular health: 400 IU-800 IU per dayDeficiency syndrome in adults: 200 IU-400 IU per dayDeficiency syndrome in children: 200 IU per dayThalassemia: 800 IU per daySickle-cell anemia: 400 IU per dayBetterment of skin & hair: 200 IU-400 IU per day (Topical use is also established for beautification)Chronic cold in adults: 200 IU per day

Interaction
Vitamin E may impair the absorption of Vitamin A & function of Vitamin K and potentiates the effect of Warfarin.

Contradiction
No known contraindications found.

Side Effect
Overdosage (>1 gm) have been associated with minor side effects, including hypertension, fatigue, diarrhea and myopathy.

Pregnancy
Vitamin E is safe in pregnancy and lactation, when used as recommended doses. Higher doses are not established.

Precaution
It may increase the risk of thrombosis in some patients, such as those taking estrogens.

Overdose

Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.