Indications
This combination may be used in-
- Chronic pains like sciatica
- Lumbago
- Trigeminal neuralgia
- Facial paralysis
- Optic neuritis
- As well as neuropathy & cardiac complications.
Therapeutic Class
Specific combined vitamin preparations
Pharmacology
This is a combined preparation of Vitamin B1 (Thiamine Mononitrate), Vitamin B6 (Pyridoxine Hydrochloride) and Vitamin B12 (Cyanocobalamin). These vitamins play an essential role as co-enzyme in the metabolism of nervous system. supports the regeneration of nerve fibers and myelin sheath by activation of the nerve cell metabolism and the natural repair mechanism.
Dosage & Administration
Tablets: 1 to 3 tablets per day or as directed by the physician.
Injection: Ampules are preferably injected intramuscularly (deep intragluteal). In severe cases 1 ampoule daily until the acute symptoms subside. For milder cases and follow up therapy 2 to 3 ampoules per week.
Injection: Ampules are preferably injected intramuscularly (deep intragluteal). In severe cases 1 ampoule daily until the acute symptoms subside. For milder cases and follow up therapy 2 to 3 ampoules per week.
Interaction
Vitamin B6 (Pyridoxine Hydrochloride) reduces therapeutic effect of Levodopa but it does not occur if a dopa decarboxylase inhibitor is also given. Neomycin, Chloramphenicol, Aminosalisylic acid & H2 receptor antagonist may reduce Vitamin B12 absorption.
Contraindications
It should not be used in patients with known hypersensitivity to Thiamine, Cobalt or any other component of these preparations.
Side Effects
Very rarely hypersensitive reaction and sensitivity disturbance may occur.