Stomach Care

Omeprazole is indicated for the treatment of- Gastric and duodenal ulcer NSAID-associated duodenal and gastric ulcer As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer Gastro-esophageal reflux disease Long-term management of acid reflux disease Acid-related dyspepsia Severe ulcerating reflux esophagitis Prophylaxis of acid aspiration during general anesthesia Zollinger-Ellison syndrome Helicobacter pylori-induced peptic ulcer.

MUPS is abbreviation for Multiple-Unit Pellet System. However, from pharmaceutical industry and research perspective, the term in general refers to MUPS compacted into tablets. Thus, the resulting tablets prepared by compaction of modified release coated multiparticulates or pellets are called as MUPS. It is the more recent and challenging technology that combines the advantages of both tablets and pellet filled capsules in one dosage form.MUPS ensure rapid and uniform gastric emptying and subsequently uniform drug dissolution of pellets in the gastrointestinal tract due to their small size and larger surface, uniform drug absorption is facilitated which results in consistent and controlled pharmacological action.A further reduction in inter- and intra-subject variability in drug absorption and clinical response is facilitated since the number of pellets per MUPS dosage form is much more than a conventional pellet-filled capsule and possibility of dose dumping(in stomach) and incomplete drug release is further minimized.

Each capsule contains-

• Lactobacillus acidophilus (2 billion)
• Lactobacillus bulgaricus (1 billion)
• Bifidobacterium bifidum (1 billion) as a 4 billion probiotic combination and
• Fructo-oligosaccharides (100 mg).