Stomach Care

Esomeprazole is indicated: Treatment of Gastroesophageal Reflux Disease (GERD) Healing of erosive esophagitis Maintenance of healing of erosive esophagitis Symptomatic Gastroesophageal Reflux Disease (GERD) Reduction of NSAID-associated gastric ulcer H. pylori eradication (Triple therapy) Zollinger-Ellison syndrome…?

Esomeprazole is indicated: Treatment of Gastroesophageal Reflux Disease (GERD) Healing of erosive esophagitis Maintenance of healing of erosive esophagitis Symptomatic Gastroesophageal Reflux Disease (GERD) Reduction of NSAID-associated gastric ulcer H. pylori eradication (Triple therapy) Zollinger-Ellison syndrome…?

Esomeprazole is indicated: Treatment of Gastroesophageal Reflux Disease (GERD) Healing of erosive esophagitis Maintenance of healing of erosive esophagitis Symptomatic Gastroesophageal Reflux Disease (GERD) Reduction of NSAID-associated gastric ulcer H. pylori eradication (Triple therapy) Zollinger-Ellison syndrome…?

Cerebral circulatory disorders: Prophylaxis and maintenance therapy for symptoms of cerebral vascular spasms and arteriosclerosis such as : dizziness, ear buzzing (tinnitus), vascular headache, unsociability and irritability, fatigue, sleep rhythm disorders such as premature awakening, involutional depressions, loss of memory and lack of concentration, incontinence and other disorders due to aging. Sequelae of cerebral and cranial trauma. Postapoplectic disorders. Migraine. Peripheral circulatory disorders: Prophylaxis and maintenance therapy for symptoms of vascular spasms and arteriosclerosis (obliterating arteritis, thromboangitis obliterans, Raynaud's disease, diabetes, acrocyanosis pernio, etc.) such as intermittent claudication, trophic disturbances, pregangrene, trophic and varicose ulcers, paraesthesia, nocturnal cramps, cold extremities.Disorders of balance: Prophylaxis and maintenance therapy for symptoms of labyrinthine arteriosclerosis; vestibular irritability;Meniere's syndrome such as vertigo, dizziness, giddiness, syncopal attacks, tinnitus, nystagmus, nausea and vomiting. Prophylaxis of motion sickness.

MUPS is abbreviation for Multiple-Unit Pellet System. However, from pharmaceutical industry and research perspective, the term in general refers to MUPS compacted into tablets. Thus, the resulting tablets prepared by compaction of modified release coated multiparticulates or pellets are called as MUPS. It is the more recent and challenging technology that combines the advantages of both tablets and pellet filled capsules in one dosage form.MUPS ensure rapid and uniform gastric emptying and subsequently uniform drug dissolution of pellets in the gastrointestinal tract due to their small size and larger surface, uniform drug absorption is facilitated which results in consistent and controlled pharmacological action.A further reduction in inter- and intra-subject variability in drug absorption and clinical response is facilitated since the number of pellets per MUPS dosage form is much more than a conventional pellet-filled capsule and possibility of dose dumping(in stomach) and incomplete drug release is further minimized.

Pantoprazole is indicated where suppression of acid secretion has therapeutic benefit; i.e?ÿ Peptic ulcer diseases Gastroesophageal reflux diseases Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs) Eradication of Helicobacter pylori (in combination with antibiotics) Zollinger-Ellison Syndrome