Indication
This Cream is indicated for the treatment of corticosteroid-responsive dermatoses when complicated by infections caused by bacteria and fungi. This?is also effective in the treatment of tinea pedis, tinea cruris & tinea corporis, acute and chronic eczema.
Pharmacology
This?Cream combines the anti-inflammatory, antipruritic and vasoconstrictive actions of Betamethasone Dipropionate with the broad spectrum antifungal activity of Clotrimazole and the wide-spectrum bactericidal antibiotic activity of Gentamicin Sulfate. Clotrimazole appears to act on the fungal cell membrane, causing leakage of cell contents. Gentamicin provides highly effective topical treatment in primary and secondary bacterial infections of the skin.
Dosage
Apply gently into the affected skin areas twice daily. Duration of therapy varies depending upon the extent and location of disease and patient response. For effective treatment, This?Cream should be applied regularly.
Interaction
Concomitant use with nephrotoxic drugs including other aminoglycosides, vancomycin and some of cephalosporins; or ototoxic drugs such as ethacrynic acid and furosemide may increase the risk of toxicity.
Contradiction
This?Cream is contraindicated in those patients with a history of sensitivity reactions to any of its components.
Side Effect
Adverse reactions have been reported very rarely and include hypochromia, burning, erythema, exudation etc.
Pregnancy
Since safety of topical corticosteroid in pregnant women has not been established, it should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. A decision should be made to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the lactating mother.
Precaution
Do not combine with any other product containing corticosteroid. Not for application to the face, avoid contact with eyes. Not for prolonged use or use in extensive areas, under an occlusive dressing, open wound, injured areas, exterior genital areas and skin folds.
Overdose
Storage